Process for the preparation of omeprazole

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 401/12 (2006.01) C07D 405/14 (2006.01) C07D 413/14 (2006.01) C07D 417/14 (2006.01) C07D 471/04 (2006.01)

Patent

CA 2078517

Omeprazole, an anti-ulcer agent having the formula Ia: (see formula Ia) is prepared by treating a mixture of pyrmetazole, having the formula IIa: (see formula IIa) in a solvent with magnesium monoperoxyphthalate, in an amount sufficient to convert pyrmetazole to omeprazole.

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