Therapeutic methods and compositions involving isoflav-3-ene...

A - Human Necessities – 61 – K

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A61K 31/352 (2006.01) A61K 31/35 (2006.01) A61P 9/00 (2006.01) A61P 19/00 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2478392

Methods for the treatment of diseases associated with aberrant cell survival, aberrant cell proliferation, abnormal cell migration, abnormal angiogenesis, abnormal estrogen/androgen balance, dysfunctional or abnormal steroid genesis, degeneration including degenerative changes within blood vessel walls, inflammation, or immunological imbalances utilising isoflav-3-ene and isoflavan compounds of the general formula (II) are described. Compositions and uses involving isoflav-3-ene and isoflavan compounds are also described.

L'invention concerne des procédés de traitement de maladies associées à une survie cellulaire aberrante, à une prolifération cellulaire aberrante, à une migration cellulaire anormale, à une angiogenèse anormale, à un équilibre oestrogène/androgène, à une genèse stéroïdienne dysfonctionnelle ou anormale, à une dégénérescence, y compris des modification dégénératives des parois des vaisseaux sanguins, les inflammations ou les déséquilibres immunologiques, procédés selon lesquels on utilise des composés isoflav-3-ène et isoflavan correspondant à la formule générale (II). L'invention concerne également des compositions contenant des composés isoflav-3-ène et isoflavan, ainsi que leurs utilisations.

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