Platelet cell adhesion molecule and variants thereof

Details Platelet cell adhesion molecule and variants thereof Platelet cell adhesion molecule and variants thereof

C - Chemistry, Metallurgy

12

N

530/13, 530/7.04

C12N 15/12 (2006.01) A61K 31/70 (2006.01) C07H 21/00 (2006.01) C07K 7/04 (2006.01) C07K 14/705 (2006.01) C07K 16/28 (2006.01)

Patent

CA 2023561

ABSTRACT OF THE DISCLOSURE A glycoprotein, PECAM-1, and variants thereof can be obtained by expression in a transformed host cell of a polynucleotide coding for the glycoprotein or a variant polypeptide. PECAM-l can also be isolated from cellular sources. An antibody specific for PECAM-l or a PECAM variant can be produced via recombinant techniques, or can be obtained from a hybridoma.

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