Self-assembling, collagen based material for corneal...

Details Self-assembling, collagen based material for corneal... Self-assembling, collagen based material for corneal...

A - Human Necessities

61

L

A61L 27/56 (2006.01) A61F 2/14 (2006.01)

Patent

CA 2646074

The present invention discloses a material derived from sea cucumber collagen fibrils for use in corneal replacements or as an implantable contact lens. The present invention also discloses a method for producing the material. The collagen fibrils are centrifuged into orthogonal stacks of lamellae comprised of aligned fibrils. The resulting structure is a transparent film of arbitrary thickness very similar in structure to mammalian corneal tissue.

La présente invention décrit un matériau dérivé de fibrilles de collagène de concombre de mer à utiliser pour des remplacements de cornée ou en tant que lentille de contact implantable. La présente invention décrit aussi un procédé pour produire le matériau. Les fibrilles de collagène sont centrifugées en piles orthogonales de lamelles composées de fibrilles alignées. La structure résultante est un film transparent d'une épaisseur arbitraire très similaire en structure au tissu cornéen des mammifères.

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