C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/11 (2006.01) A61K 31/7088 (2006.01)
Patent
CA 2730641
The present invention relates to oligomer compounds (oligomers), which target GLI2 mRNA in a cell, leading to reduced expression of GLI2. Reduction of GLI2 expression is beneficial for the treatment of certain medical disorders, such as hy-perproliferative disorders, such as cancer.
La présente invention porte sur des composés oligomères (oligomères) qui ciblent l'ARNm de GLI2 dans une cellule, conduisant à une expression réduite de GLI2. Une réduction de l'expression de GLI2 est avantageuse pour le traitement de certains troubles médicaux, tels que les troubles hyperprolifératifs comme le cancer.
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Enzon Pharmaceuticals Inc.
Santaris Pharma A/s
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