Heterocyclic compounds and uses thereof in the treatment of...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 239/90 (2006.01) A61K 31/4523 (2006.01) A61K 31/517 (2006.01) C07D 311/22 (2006.01) C07D 401/06 (2006.01) C07D 401/12 (2006.01) C07D 403/06 (2006.01) C07D 403/12 (2006.01) C07D 405/06 (2006.01) C07D 405/12 (2006.01) C07D 413/06 (2006.01) C07D 417/12 (2006.01) C07D 471/04 (2006.01) C07D 473/06 (2006.01) C07D 473/30 (2006.01)

Patent

CA 2680789

Novel heterocyclic compounds, which exhibit a dopamine receptor (preferably a D4 receptor) agonistic activity, and/or a PDE5 inhibitory activity, processes of preparing same, pharmaceutical compositions containing same and uses thereof in the treatment of sexual disorders such as decreased libido, orgasm disorder and erectile dysfunction are disclosed.

La présente invention concerne des nouveaux composés hétérocycliques, qui présentent une activité agonistique de récepteur de dopamine (de préférence un récepteur D4), et/ou une activité d'inhibition de PDE5, leurs procédés de préparation, des compositions pharmaceutiques les contenant et leurs utilisations dans le traitement de troubles sexuels tels qu'une diminution de la libido, un trouble de l'orgasme et un problème d'érection.

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