Use of angiogenin or angiogenin agonists for treating...

A - Human Necessities – 61 – K

Patent

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Details

A61K 38/19 (2006.01) A61K 35/12 (2006.01) A61P 3/00 (2006.01) A61P 17/02 (2006.01) A61P 21/00 (2006.01) A61P 25/28 (2006.01) C07K 14/515 (2006.01)

Patent

CA 2723987

The invention provides a method of treating a disorder characterised by elevated or dysregulated myostatin, disorders where the interaction between follistatin and angiogenin can be used to improve function in tissues, neurological diseases or disorders, spinal injuries or diseases, bone diseases or disorders, diseases involving glucose homeostasis, wound healing, neuroprotection, nervous system functional support or managing metabolic diseases, the method comprising administering an effective amount of angiogenin or an angiogenin agonist. Compositions and neutraceuticals comprising angiogenin are also provided.

L'invention concerne un procédé pour traiter un trouble caractérisé par un taux de myostatine élevé ou anormal, des troubles dans lesquels l'interaction entre la follistatine et l'angiogénine peut être utilisée pour améliorer la fonction dans les tissus, des maladies ou des troubles neurologiques, des maladies ou des traumatismes médullaires, des maladies ou des troubles des os ou des maladies caractérisées par une homéostasie du glucose, ou pour la cicatrisation, la neuroprotection, le soutien des fonctions du système nerveux ou la gestion de maladies métaboliques, ce procédé consistant à administrer une dose efficace d'angiogénine ou d'un agoniste de l'angiogénine. L'invention concerne également des compositions et des nutraceutiques comprenant de l'angiogénine.

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