Phenylacetamides suitable as protein kinase inhibitors

Details Phenylacetamides suitable as protein kinase inhibitors Phenylacetamides suitable as protein kinase inhibitors

C - Chemistry, Metallurgy

07

D

C07D 471/04 (2006.01) A61K 31/4184 (2006.01) A61K 31/4188 (2006.01) A61P 35/00 (2006.01) A61P 35/02 (2006.01) C07D 235/04 (2006.01)

Patent

CA 2603941

The invention relates to compounds of the formula (I) wherein the moieties R1 , R2, R3, R9, R10 and Q and X, Y and Z are as defined in the specification, and salts thereof; as well as their use, methods of use for them and method of their synthesis, and the like. The compounds are protein kinase inhibitors and can, inter alia, be used in the treatment of various proliferative diseases.

L'invention concerne des composés représentés par la formule (I), dans laquelle les fractions R1, R2, R3, R9, R10 et Q ainsi que X, Y et Z sont tels que définis dans la spécification, et des sels desdits composés ; ainsi que leur utilisation, des méthodes d'utilisation de ces derniers et des méthodes de synthèse de ces derniers, et analogues. Lesdits composés sont des inhibiteurs de protéines kinases et peuvent, entre autres, être utilisés dans le traitement de diverses maladies prolifératives.

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