Tetracyclic indole derivatives as antiviral agents

Details Tetracyclic indole derivatives as antiviral agents Tetracyclic indole derivatives as antiviral agents

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) A61K 31/407 (2006.01) A61P 31/00 (2006.01) C07D 223/18 (2006.01)

Patent

CA 2585113

The present invention relates to tetracyclic indole compounds of formula (I); wherein R1, R2, R14, R15, A, Ar, Y and Z are defined herein, and pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising them, and their use for the treatment or prevention of infection by hepatitis C virus.

La présente invention concerne des composés d'indole tétracycliques de formule (I) dans laquelle R1, R2, R14, R15, A, Ar, Y et Z sont tels que définis, des sels de ceux-ci, acceptables d'un point de vue pharmaceutique, ainsi que des compositions pharmaceutiques comprenant lesdits composés et leur utilisation pour traiter ou prévenir une infection par le virus de l'hépatite C.

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