A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/22 (2006.01) A61K 9/16 (2006.01) A61K 9/20 (2006.01) A61K 9/28 (2006.01) A61K 9/50 (2006.01) A61K 9/52 (2006.01) A61K 31/56 (2006.01) A61K 45/08 (2006.01) A61K 47/32 (2006.01) A61K 47/36 (2006.01)
Patent
CA 2244421
Treatment of certain diseases of the colon by orally ingesting a suitable dosage form having a composition containing a plurality of rigid cross-linked polymer beads, each defining a substantially noncollapsible internal pore network, and a therapeutically effective amount of an active agent or drug in said pore network. The dosage form is treated with a polysaccharide, such as pectin, which is specifically attacked by colonic bacteria to permit drug release in the colon.
Traitement de certaines maladies du colon par ingestion orale d'une forme galénique appropriée constituée d'une composition contenant une pluralité de billes dures de polymère réticulé qui définissent chacune un réseau de pores interne à effondrement sensiblement nul et une quantité thérapeutiquement efficace d'un agent ou d'un médicament actif contenu dans ledit réseau de pores. La forme galénique est traitée avec un polysaccharide, tel que de la pectine, qui est spécifiquement attaqué par les bactéries du colon paour permettre la libération du médicament dans le colon.
Berliner David L.
Nacht Sergio
Advanced Polymer Systems Inc.
Dennison Associates
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