Medecines of ulcerative colitis

A - Human Necessities – 61 – K

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A61K 31/4245 (2006.01) A61K 31/4355 (2006.01) A61K 31/4365 (2006.01) A61K 31/437 (2006.01) A61K 31/4439 (2006.01) A61K 31/4725 (2006.01) A61K 31/513 (2006.01) A61K 31/5377 (2006.01) A61K 31/55 (2006.01) A61K 38/05 (2006.01) A61P 1/00 (2006.01) A61P 1/04 (2006.01) A61P 43/00 (2006.01) C07D 413/12 (2006.01) C07D 413/14 (2006.01) C07D 471/04 (2006.01) C07D 487/04 (2006.01) C07D 487/06 (2006.01) C07D 491/048 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2423423

Prophylactic and/or therapeutic drugs against ulcerative colitis, which include five-member heterocyclic compounds represented by the formula (I) or these nontoxic salts as active principle, Image (wherein Z represents the group containing .alpha.-aminocarbonyl group, R1 represents (1) substituted alkyl, alkenyl or alkynyl groups, (2)OH, (3)amino, (4)alkylamino, (5)dialkylamino, etc., X and Y represent oxygen atom, sulfur atom or substituted nitrogen atom.)

L'invention porte sur des remèdes contre les troubles inflammatoires des intestins contenant comme principe actif des composés hétérocycliques à 5 éléments (ou leurs sels non toxiques) de formule générale (I) dans laquelle: Z représente un groupe contenant de l' alpha -aminocarbonyle; R<1> représente: (1) alkyle, alcényle, ou alkynyle, (2) OH, (3) amino, (4) alkylamino, (5) dialkylamino, etc.; et X et Y représentent chacun O, S ou un atome N substitué.

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