A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/39 (2006.01) A61K 31/70 (2006.01) A61K 31/7028 (2006.01) A61K 31/739 (2006.01)
Patent
CA 2697993
The immunogenicity of vaccines is enhanced by co-administering a synthetic glycolipid, designated PBS-57, with the vaccine. PBS-57 has the ability to stimulate both a cell-mediated and humoral immune response. Co-administration of PBS-57 with a vaccine may be used in methods to stimulate one or more of a humoral immune response, a CD4+ T cell response, and a CD8+ cytotoxic T cell response.
La présente invention concerne des procédés permettant de renforcer l'immunogénicité d'un vaccin grâce à la co-administration d'un glycolipide de synthèse, connu sous le nom de PBS-57, et du vaccin proprement dit. Le PBS-57 a la capacité de stimuler à la fois une réponse immunitaire à médiation cellulaire et une réponse immunitaire humorale. On peut avoir recours à la co-administration de PBS-57 et d'un vaccin dans le cadre de procédés visant à stimuler une ou plusieurs réponses immunitaires humorales, la production de lymphocytes T CD4+ et la production de lymphocytes T CD8+ cytotoxiques.
Robic
Wittycell
LandOfFree
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