Monoclonal antibodies for neutralizing anthrax toxin

Details Monoclonal antibodies for neutralizing anthrax toxin Monoclonal antibodies for neutralizing anthrax toxin

C - Chemistry, Metallurgy

12

N

C12N 15/13 (2006.01) A61K 39/40 (2006.01) A61P 31/04 (2006.01) C07K 16/12 (2006.01) C12N 5/16 (2006.01) G01N 33/569 (2006.01) C07K 14/32 (2006.01) C07K 16/40 (2006.01)

Patent

CA 2679676

Isolated monoclonal antibodies that bind and/or neutralize anthrax protective antigen (PA) are disclosed as well as hybridomas secreting such antibodies. The invention also provides anti-PA fragments of the antibodies of the invention and recombinantly produced antibodies. Also provided are pharmaceutical compositions containing the antibodies or antibody fragments and uses and methods involving same.

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