Method and apparatus for determining anticoagulant therapy...

G - Physics – 01 – N

Patent

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G01N 33/49 (2006.01) G01N 33/86 (2006.01)

Patent

CA 2339006

A method and apparatuses are disclosed for determining an anticoagulant therapy factor (ATF), a corrected anticoagulant therapy factor and a modified anticoagulant therapy factor, all selectively used for monitoring oral anticoagulant therapy to help prevent excessive bleeding or deleterious blood clots that might otherwise occur before, during or after surgery. The anticoagulant therapy factor, the corrected anticoagulant therapy factor, and a modified anticoagulant therapy factor are based upon disclosed methods for determining the fibrinogen tranformation rate which, in turn, is dependent on a maximum acceleration point for fibronogen conversion.

Cette invention concerne un procédé et des appareils qui permettent de déterminer un facteur de thérapie d'anticoagulation (ATF), un facteur de thérapie d'anticoagulation corrigé, ainsi qu'un facteur de thérapie d'anticoagulation modifié. Chacun de ces facteurs est utilisé de manière sélective afin de contrôler une thérapie d'anticoagulation orale, et de mieux prévenir les saignements excessifs ou les caillots sanguins délétères pouvant survenir avant, pendant ou après une opération chirurgicale. Le facteur de thérapie d'anticoagulation, le facteur de thérapie d'anticoagulation corrigé ainsi que le facteur de thérapie d'anticoagulation modifié reposent sur des procédés qui permettent de déterminer la vitesse de transformation fibrinogène qui dépend, à son tour, du point d'accélération maximale de la conversion fibrinogène.

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