Method of treating cancer using a combination comprising...

A - Human Necessities – 61 – K

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A61K 31/498 (2006.01) A61K 31/513 (2006.01) A61K 31/7068 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2544320

Methods of treating a human body for cancer are provided. In one aspect, a therapeutic amount of capecitabine is administered in combination with ET-743 in a dose range between 0.75 and 1.4 mg/m2 for Et-743. In a related aspect, an effective therapeutic amount of ET-743 is administered in combination with capecitabine in a dose range between 1500 to 2500 mg/m/day for capecitabine.

La présente invention concerne des méthodes permettant de traiter un cancer chez un patient humain. Dans un aspect de cette invention, une quantité thérapeutique de capécitabine est administrée conjointement avec la ET-743 (ectéinascidine) dans une marge posologique comprise entre 0,75 et 1,4 mg/m?2¿ pour la ET-743. Dans un mode de réalisation associé, une quantité thérapeutique efficace de ET-743 est administrée conjointement avec la capécitabine dans une marge posologique comprise entre 1500 et 2500 mg/m?2¿/jour pour la capécitabine.

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