Immunoglobulins comprising predominantly a...

Details Immunoglobulins comprising predominantly a... Immunoglobulins comprising predominantly a...

C - Chemistry, Metallurgy

07

K

C07K 16/00 (2006.01)

Patent

CA 2573745

The present invention relates to immunoglobulin glycoprotein compositions having predominant N-glycan structures on an immunoglobulin glycoprotein which confer a specific effector function. Additionally, the present invention relates to pharmaceutical compositions comprising an antibody having a particular enriched N-glycan structure, wherein said N-glycan structure is GlcNAc2Man3GlcNAc2.

Cette invention se rapporte à des compositions de glycoprotéines d~immunoglobulines à prédominance de structures N-glycanes sur une glycoprotéine d~immunoglobuline, qui confèrent une fonction effectrice spécifique. Cette invention concerne également des compositions pharmaceutiques contenant un anticorps ayant une structure N-glycane enrichie donnée, ladite structure N-glycane étant GlcNAc2Man3GlcNAc2.

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