Process for preparing amorphous...

Details Process for preparing amorphous... Process for preparing amorphous...

C - Chemistry, Metallurgy

07

D

C07D 405/06 (2006.01) C07D 207/34 (2006.01)

Patent

CA 2551549

The invention relates to a process of preparing amorphous (4R-cis)-6-[2-[3- phenyl-~4-(phenylcarbamoyl)-2-(4-fluorophenyl)-5-(1-methylethyl)-pyrrol-1-yl]- ethyl]-2,2-~dimethyl-[1,3]-dioxane-4-yl-acetic acid - tertiary butyl ester which is a useful pharmaceutical intermediate in the preparation of atorvastatin salts.

L'invention concerne un procédé pour préparer un composé amorphe d'acide (4R-cis)-6-[2-[3-phényl-4-(phénylcarbamoyl)-2-(4-fluorophényl)-5-(1-méthyléthyl)-pyrrol-1-yl]-éthyl]-2,2-diméthyl-[1,3]-dioxane-4-yl-acétique butyl ester tertiaire qui peut servir de produit intermédiaire pharmaceutique dans la préparation de sels d'atorvastatine.

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