A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/00 (2006.01) A61K 33/24 (2006.01)
Patent
CA 2580805
Methods for enhancing the immune response of a subject to an immunoeffector, and methods of enhancing interleukin-12 production, which are effected by administering an amount of the immunoeffector and an effective adjuvanting amount of a tellurium-containing compound are provided. The enhanced immune response may be a cell-mediated or a humoral immune response. A pharmaceutical composition, which comprises the tellurium-containing compound, the immunoeffector and a pharmaceutically acceptable carrier is also provided. Use of a tellurium-containing compound as an adjuvant for immunization is also provided.
L'invention concerne des méthodes permettant d'augmenter la réponse immunitaire d'un sujet par rapport à un effecteur immunitaire, ainsi que des méthodes permettant d'augmenter la production de l'interleukine-12, consistant à administrer au sujet une dose de l'effecteur immunitaire et une dose utile d'un adjuvant à base de tellure. L'augmentation de la réponse immunitaire peut apparaître sous forme de réponse immunitaire cellulaire ou humorale. L'invention concerne également une composition pharmaceutique comprenant un composé à base de tellure, l'effecteur immunitaire et un excipient de qualité pharmaceutique. L'invention concerne également l'utilisation d'un composé à base de tellure comme un adjuvant pour l'immunisation.
Albeck Michael
Sredni Benjamin
Biomas Ltd.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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