C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/40 (2006.01) G01N 33/537 (2006.01)
Patent
CA 2599669
It is intended to establish an immunoassay method for human OPRT. An assay method for human orotate phosphoribosyltransferase protein using an anti-human orotate phosphoribosyltransferase antibody that recognizes an epitope present in an amino acid region between positions 86 and 108 from the N-terminus of human orotate phosphoribosyltransferase and an anti-human orotate phosphoribosyltransferase antibody that recognizes an epitope present in an amino acid region between positions 454 and 474 from the N-terminus of human orotate phosphoribosyltransferase in combination.
L~invention a pour but d~établir un procédé d~immunodosage de l~OPRT humaine. L~invention consiste en un procédé de dosage de la protéine orotate phosphoribosyltransférase humaine utilisant un anticorps anti-orotate phosphoribosyltransférase humaine qui reconnaît un épitope présent dans une région d~acides aminés entre les positions 86 et 108 à partir de la terminaison N d~une orotate phosphoribosyltransférase humaine et un anticorps anti-orotate phosphoribosyltransférase humaine qui reconnaît un épitope dans une région d~acides aminés entre les positions 454 et 474 à partir de la terminaison N d~une orotate phosphoribosyltransférase humaine en combinaison.
Sakamoto Kazuki
Sugimoto Yoshikazu
Gowling Lafleur Henderson Llp
Taiho Pharmaceutical Co. Ltd.
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