Stents comprising biodegradable polymers associated with...

A - Human Necessities – 61 – L

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A61L 27/44 (2006.01) A61K 9/14 (2006.01) A61K 31/192 (2006.01) A61K 31/337 (2006.01) A61K 31/436 (2006.01) A61K 31/519 (2006.01) A61K 31/60 (2006.01) A61L 27/14 (2006.01) A61L 27/54 (2006.01)

Patent

CA 2506319

Medical devices with at least one surface comprising a polymer or polymers on the surface are provided. The polymer or polymers are capable of breaking down (e.g., including, but not limited to, hydrolyzing) in the physiologic milieu to form an active agent or agents under physiologic conditions, and can contain other active agents dispersed within or appended to the polymer matrix. Methods of delivering an active agent to an interior surface of a vein or artery are also provided.

L'invention concerne des dispositifs médicaux qui comprennent au moins une surface sur laquelle un ou plusieurs polymères est/sont prévu(s). Le ou les polymères peuvent se décomposer (notamment, mais pas exclusivement, par hydrolyse) dans le milieu physiologique afin de former un ou plusieurs agents actifs dans des conditions physiologiques, et peuvent contenir d'autres agents actifs dispersés dans la matrice polymère ou fixés à celle-ci. Des procédés d'apport d'agent actif à la surface intérieure d'une veine ou d'une artère sont également décrits.

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