Vascular endothelial growth factor (vegf) nucleic acid...

Details Vascular endothelial growth factor (vegf) nucleic acid... Vascular endothelial growth factor (vegf) nucleic acid...

A - Human Necessities

61

K

A61K 47/48 (2006.01) A61K 47/30 (2006.01) A61K 47/44 (2006.01) A61P 9/10 (2006.01) A61P 35/00 (2006.01) C07H 21/02 (2006.01) G01N 33/50 (2006.01) C12N 15/88 (2006.01)

Patent

CA 2535449

This invention discloses a method for preparing a complex comprised of a VEGF Nucleic Acid Ligand and a Non-Immunogenic, High Molecular Weight Compound or Lipophilic Compound by identifying a VEGF Nucleic Acid Ligand by SELEX methodology and associating the VEGF Nucleic Acid Ligand with a Non- Immunogenic, High Molecular Weight Compound or Lipophilic Compound. The invention further discloses Complexes comprising one or more VEGF Nucleic Acid Ligands in association with a Non-Immunogenic, High Molecular Weight Compound or Lipophilic Compound. The invention further includes a Lipid construct comprising a VEGF Nucleic Acid Ligand or Complex and methods for making the same.

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