Human bone derived insulin like growth factor binding protein

Details Human bone derived insulin like growth factor binding protein Human bone derived insulin like growth factor binding protein

C - Chemistry, Metallurgy

07

K

C07K 14/47 (2006.01) A61K 38/17 (2006.01) A61K 38/30 (2006.01) A61K 47/48 (2006.01) G01N 33/566 (2006.01) G01N 33/74 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2107475

2107475 9218154 PCTABS00016 Purified and isolated compositions of a binding protein for insulin-like growth factors (IGFs) I and II are provided. The binding protein, known as human bone derived IGF binding protein (hBD-IGFBP), potentiates the proliferative effects of IGF-II upon bone cells. Diagnostic assays are also provided for hBD-IGFBP, as well as pharmaceutical compositions and methods for treatment of bone disorders, wound healing, skin repair, and means for modulating IGF activity in bone.

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