C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/165 (2006.01) A61K 38/08 (2006.01) A61K 38/10 (2006.01) A61K 38/16 (2006.01) A61K 39/215 (2006.01) A61K 39/385 (2006.01) A61K 47/42 (2006.01) A61K 47/48 (2006.01) A61P 31/14 (2006.01) C07K 7/06 (2006.01) C07K 7/08 (2006.01) C07K 17/02 (2006.01) C07K 19/00 (2006.01)
Patent
CA 2524209
The invention provides compositions and methods that are useful for preventing and treating a coronavirus infection in a subject. More specifically, the invention provides peptides and conjugates and pharmaceutical compositions containing those peptides and conjugates that block fusion of a coronavirus, such as the SARS virus, to a target cell. This blocking mechanism prevents or treats a coronavirus infection, such as a SARS infection, in a subject, such as a human subject.
L'invention concerne des compositions et des méthodes utiles pour prévenir et traiter une infection à coronavirus chez un sujet. Plus spécifiquement, l'invention concerne des peptides et des conjugués ainsi que des compositions pharmaceutiques contenant lesdits peptides et conjugués qui bloquent la fusion d'un coronavirus, tel que le virus du SRAS, avec une cellule cible. Ledit mécanisme de blocage permet de prévenir ou de traiter une infection à coronavirus, tel qu'une infection par le SRAS, chez un sujet, tel qu'un sujet humain.
Erickson John W.
Silva Abelardo
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Sequoia Pharmaceuticals Inc.
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