Antiangiogenesis therapy of autoimmune disease in patients...

Details Antiangiogenesis therapy of autoimmune disease in patients... Antiangiogenesis therapy of autoimmune disease in patients...

A - Human Necessities

61

K

A61K 39/395 (2006.01) A61K 31/519 (2006.01) A61K 38/19 (2006.01) A61P 19/02 (2006.01) A61P 29/00 (2006.01) A61P 37/02 (2006.01) C07K 16/22 (2006.01) C07K 16/28 (2006.01)

Patent

CA 2587932

The present application describes therapy with angiogenesis antagonists such as anti-VEGF antibodies. In particular, the application describes the use of such antagonists to treat autoimmune disease in a patient who has failed prior treatment such as treatment with DMARDs or TNF.alpha.-inhibitors.

L'invention concerne une thérapie faisant appel à des antagonistes angiogéniques, par exemple des anticorps anti-VEGF. Plus précisément, l'invention concerne l'utilisation de ces antagonistes pour traiter une maladie auto-immune chez un patient qui n'a pas réagi un traitement antérieur, par exemple un traitement faisant appel à des DMARD ou à des inhibiteurs de TNF.alpha..

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