Method for examining neurovirulence of polio virus

Details Method for examining neurovirulence of polio virus Method for examining neurovirulence of polio virus

C - Chemistry, Metallurgy

12

Q

C12Q 1/70 (2006.01) C07K 14/705 (2006.01) C12N 15/85 (2006.01) C12Q 1/02 (2006.01) G01N 33/15 (2006.01) G01N 33/48 (2006.01)

Patent

CA 2163229

The present invention relates to a method of examining the neurovirulence of a polio virus, which comprises inoculating a polio virus into the spinal cord of a transgenic non-primate vertebrate animal with a gene for a polio virus receptor introduced therein.

Un procédé de test de la neurotoxicité d'un vaccin contre le virus poliomyélitique consiste à inoculer le vaccin dans la moelle épinière d'un vertébré transgénique non primate dans lequel on a introduit des gènes récepteurs de virus poliomyélitique.

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