Method of modulating gene transcription

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/63 (2006.01) A61K 31/00 (2006.01) A61K 33/00 (2006.01) A61K 38/00 (2006.01) A61K 39/395 (2006.01) A61K 48/00 (2006.01) C12Q 1/02 (2006.01) G01N 33/50 (2006.01)

Patent

CA 2529677

It is an aspect of the present invention to provide a method of modulating nucleosome remodelling or gene transcription in a cell, said method comprising modulating in the cell an interaction of a methyl-CpG-binding protein with one or more subunits of a nucleosome remodelling complex.

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