C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/09 (2006.01) A01K 67/027 (2006.01) A61K 45/00 (2006.01) C07K 14/705 (2006.01) C07K 16/28 (2006.01) C12N 5/10 (2006.01) C12Q 1/02 (2006.01) G01N 33/68 (2006.01)
Patent
CA 2446708
It is intended to provide a gene and a protein participating in central nerve diseases and a method of efficiently evaluating an activity controller for the protein. A DNA comprising the base sequence represented by SEQ ID NO:1; a potential-dependent cation channel protein encoded by the DNA; an antisense nucleic acid against the DNA sequence; a method of searching for a substance controlling the channel function of the above protein with the use of the protein; and antibodies specific to the antisense nucleic acid to the DNA and the protein.
La présente invention concerne un gène et une protéine intervenant dans des affections du système nerveux central, et un procédé permettant d'évaluer un régulateur d'activité de la protéine. L'invention concerne également un ADN comprenant la séquence de base SEQ ID NO:1, une protéine de canal cation dépendant du potentiel, codée par l'ADN, un acide nucléique antisens dirigé contre la séquence ADN, un procédé permettant de rechercher une substance régulant la fonction canal de la protéine ci-dessus avec utilisation de la protéine, et des anticorps spécifiques de l'acide nucléique antisens de l'ADN et de la protéine.
Furusako Shoji
Nakamura Yusuke
Okawa Kazufumi
Sugano Sumio
Takahashi Tomohiro
Mochida Pharmaceutical Co. Ltd.
Ridout & Maybee Llp
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