Polyester/silicone coreticulate degradable by hydrolysis

C - Chemistry – Metallurgy – 08 – G

Patent

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Details

402/11, 167/153,

C08G 18/42 (2006.01) A61K 47/34 (2006.01) C08G 18/10 (2006.01) C08G 77/14 (2006.01)

Patent

CA 2037734

PRECIS DE LA DIVULGATION: La présente invention concerne un coréticulat polyester- silicone dégradable par hydrolyse qui est le produit de réaction: a) d'au moins un diorganopolysiloxane présentant par molécule des fonctions hydroxyle liées chacune aux atomes de silicium par une liaison Si-C; b) un oligomère polyester polylactique et/ou polyglycolique .alpha.,.omega. -diol; c) un polyisocyanate organique. Les coréticulats selon l'invention sont en particulier utilisables comme matrice contenant un principe actif en vue de la libération contrôlée du principe actif par simple érosion par hydrolyse de cette matrice .

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