Tricyclic compounds and method of treating herpes virus

Details Tricyclic compounds and method of treating herpes virus Tricyclic compounds and method of treating herpes virus

C - Chemistry, Metallurgy

07

D

C07D 307/91 (2006.01) A61K 31/34 (2006.01) A61P 31/22 (2006.01) C07C 211/61 (2006.01) C07C 215/88 (2006.01) C07C 217/94 (2006.01) C07D 209/88 (2006.01) C07D 211/58 (2006.01) C07D 213/38 (2006.01) C07D 221/00 (2006.01) C07D 223/22 (2006.01) C07D 279/10 (2006.01) C07D 319/24 (2006.01) C07D 327/00 (2006.01) C07D 327/08 (2006.01) C07D 333/54 (2006.01) C07D 333/76 (2006.01) C07D 405/12 (2006.01) C07D 407/12 (2006.01) C07D 409/12 (2006.01) C07D 411/12 (2006.01) C07D 497/04 (2006.01)

Patent

CA 2396560

The present invention provides a compound of the formula (I) and pharmaceutically acceptable salts having useful antiviral activity against viruses of the herpes family. In said formula, X = O, (CH2)m, S, SO, SO2, NH, NR8 or a chemical bond; Y = O, (CH2)m, S, SO, SO2, NH, NR8; Z = NH, O, NR8, S, SO, SO2. The remaining substituents are described in the specification.

L'invention concerne un composé correspondant à la formule (I) ainsi que des sels de celui-ci, acceptables sur le plan pharmacologique. Ces composés et sels possèdent une activité antivirale dirigée contre les virus de la famille de l'herpès. Dans cette formule X = O, (CH¿2?)¿m?, S, SO, SO¿2?, NH, NR¿8? ou une liaison chimique, Y = O, (CH¿2?)¿m?, S, SO, SO¿2?, NH, NR¿8? et Z = NH, O, NR¿8?, S, SO, SO¿2?. Les autres substituants possèdent les notations données dans la description.

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