Benzo-fused macrocycles promote release of growth hormone

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 487/08 (2006.01) A61K 31/55 (2006.01) C07D 487/18 (2006.01) C07D 498/08 (2006.01) C07D 513/08 (2006.01) C07D 513/18 (2006.01)

Patent

CA 2174235

There are disclosed certain novel compounds identified as benzo-fused macrocycles which promote the release of growth hormone in humans and animals. This property can be utilized to promote the growth of food animals to render the production of edible meat products more efficient, and in humans, to increase the stature of those afflicted with a lack of a normal secretion of natural growth hormone. Growth promoting compositions containing such benzo-fused macrocycles as the active ingredient thereof are also disclosed.

Sont décrits certains nouveaux composés identifiés comme des macrocycles benzo-condensés qui stimulent la libération de l'hormone de croissance chez l'homme et chez l'animal. Cette caractéristique peut être utilisée pour stimuler la croissance d'animaux de bouche pour rendre plus efficace la production de produits carnés comestibles, et chez l'homme, pour accroître la taille des sujets souffrant d'une absence de sécrétion normale de l'hormone de croissance naturelle. Sont également décrites des compositions activant la croissance et contenant comme principe actif ces macrocycles benzo-condensés.

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