Reliable detection of vancomycin-intermediate staphylococcus...

C - Chemistry – Metallurgy – 12 – Q

Patent

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Details

C12Q 1/68 (2006.01) C07K 14/31 (2006.01) C12N 15/31 (2006.01) C12Q 1/04 (2006.01) G01N 33/569 (2006.01)

Patent

CA 2665948

The present invention relates to a method for identifying a VISA strain in a sample comprising measuring SAV2095 expression levels, a kit and use of SAV2095 for same. The present invention also relates to a method for facilitating the development of an individualized treatment regimen comprising measuring the expression level of SAV2095. The present invention further relates to a method for monitoring the progression of a vancomycin treatment of an infection comprising measuring the expression level of SAV2095. The present invention also relates to the detection of Staphylococcus aureus in a sample.

La présente invention concerne un procédé d'identification d'une souche VISA dans un échantillon comprenant la mesure de niveaux d'expression de SAV2095, une trousse et l'utilisation SAV2095 pour une telle trousse. La présente invention concerne également un procédé pour faciliter le développement d'un régime de traitement individualisé comprenant la mesure du niveau d'expression de SAV2095. La présente invention concerne en outre un procédé de suivi de la progression d'un traitement par la vancomycine d'une infection comprenant la mesure du niveau d'expression de SAV2095. La présente invention concerne enfin la détection de Staphylococcus aureus dans un échantillon.

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