A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/045 (2006.01)
Patent
CA 2622001
Methods for treating and preventing middle ear infections by transmembrane administration of medicament-containing transmembrane carrier compositions comprising a chemical penetration enhancer, such as propylene glycol. The compositions are applied to the ear so as to contact the outer surface of an intact tympanic membrane to deliver the medicament across the membrane and into the middle ear. The medicaments delivered according to the methods of the invention include antibiotic, anti- viral, anti-fungal and anti- inflammatory agents that are useful in treatment and/or prophylaxis of middle ear infections and their sequelae.
Procédés de traitement et de prévention des infections de l'oreille moyenne par administration transmembranaire de compositions du type vecteur transmembranaire porteuses de médicament, renfermant un agent qui améliore la pénétration chimique, par exemple propylène glycol. On applique les compositions à l'oreille pour assurer le contact avec la surface externe d'une membrane tympanique intacte, permettant la délivrance de médicament à travers la membrane et dans l'oreille moyenne. On peut ainsi délivrer : antibiotiques, antiviraux, antifongiques et anti-inflammatoires utiles dans le traitement et/ou la prévention des infections de l'oreille moyenne et de leurs séquelles.
Campbell William R.
Johnson Roland H.
Paulsen Neil E.
Mbm Intellectual Property Law Llp
Piedmont Pharmaceuticals Llc
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