A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/365 (2006.01) A61K 31/20 (2006.01) A61K 31/203 (2006.01) A61K 45/06 (2006.01) A61P 3/10 (2006.01) A61P 5/50 (2006.01) A61P 35/02 (2006.01) A61P 43/00 (2006.01)
Patent
CA 2440979
This invention features the use of the spirolaxine of formula (I) for the treatment of those pathologies responding to the activation of the PPAR.UPSILON. receptor, such as the Type 2 insulin-resistant diabetes. This invention also features a pharmaceutical composition in which the spirolaxine of formula (I) acts as active principle in association with the all-trans retinoic acid of formula (II) for the treatment of those pathologies responding to the activation of the PPAR.UPSILON. receptor, such as the acute malignant haemopathies.
Cette invention concerne l'utilisation de spirolaxine de formule (I) pour le traitement des pathologies réagissant à l'activation du récepteur PPAR-.gamma., telles que les diabètes insulino-résistants de type 2. L'invention concerne également une composition pharmaceutique dans laquelle la spirolaxine de formule (I) agit en tant que principe actif associé à de l'acide tout-trans rétinoïque de formule (II) pour le traitement des pathologies réagissant à l'activation du récepteur PPAR-.gamma. telles que les hémopathies malignes aigües.
Pisano Claudio
Riccioni Teresa
Fetherstonhaugh & Co.
Sigma-Tau Industrie Farmaceutiche Riunite S.p.a
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