Pyrazolo¢4,3-d!pyrimidin-7-ones and...

Details Pyrazolo¢4,3-d!pyrimidin-7-ones and... Pyrazolo¢4,3-d!pyrimidin-7-ones and...

C - Chemistry, Metallurgy

07

D

C07D 487/22 (2006.01) A61K 31/52 (2006.01) A61P 15/00 (2006.01) C07D 213/80 (2006.01) C07D 471/04 (2006.01) C07D 471/14 (2006.01) C07D 473/08 (2006.01) C07D 487/04 (2006.01) C07D 487/14 (2006.01)

Patent

CA 2376844

The present invention provides a compound of formula (I): Image where Q is a group of formula: Image These compounds inhibit cyclic guanosine 3',5'-monophosphate phosphodiesterases (cGMP PDEs). More notably, the compounds are potent and selective inhibitors of the type 5 cyclic guanosine 3',5'-monophosphate phosphodiesterases and have utility therefore in a variety of therapeutic areas. In particular, the present compounds are of value for the curative or prophylactic treatment of mammalian sexual disorders.

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