Medicaments having a benzothiazolamine-2 derivative base,...

Details Medicaments having a benzothiazolamine-2 derivative base,... Medicaments having a benzothiazolamine-2 derivative base,...

C - Chemistry, Metallurgy

07

D

167/234, 260/309

C07D 277/82 (2006.01) A61K 31/425 (2006.01) C07F 7/10 (2006.01)

Patent

CA 2005592

Medications containing as an active ingredients at least one compound with the formula Image in which - either R1 represents a polyfluoroalkoxy, trifluoro-2,2,2 ethyl, pentafluorethyl, tert-butyl, trimethylsilyl or trifluoromethylthio radical and R2 and R3 represent a hydrogen atom, - or R1 represents a polyfluoroalkoxy radical, R2 represents a hydrogen atom and R3 represents an alkyl, amino, alkoxy, phenyl, phenylalkyl, dimethylamino or dialkylamino-alkylthio radical, - or R1 represents a polyfluoroalkoxy radical, R2 represents an amino radical and R3 represents a hydrogen atom, with the exception of trifluoromethoxy-6 benzothiazolamine-2 or a salt of such a compound with a mineral or organic acid, the new formula (I) compounds and their preparation.

BREVET D'INVENTION MEDICAMENTS A BASE DE DERIVES DE LA BENZOTHIAZOLAMINE-2, NOUVEAUX DERIVES ET LEUR PREPARATION RHONE-POULENC SANTE ABREGE Médicaments contenant en tant que principe actif au moins un composé de formule : Image (I) dans laquelle - soit R1 représente un radical polyfluoroalcoxy, trifluo- ro-2,2,2 éthyle, pentafluoroéthyle, tertbutyle, triméthylsilyle ou trifluorométhylthio et R2 et R3 représentent un atome d'hydrogène, - soit R1 représente un radical polyfluoroalcoxy, R2 représente un atome d'hydrogène et R3 représente un radical alkyle, amino, alcoxy, phényle, phénylalkyle, diméthylamino ou dialkylamino- alkylthio, - soit R1 représente un radical polyfluoroalcoxy, R2 re- présente un radical amino et R3 représente un atome d'hydrogène, à l'exception de la trifluorométhoxy-6 benzothiazolamine-2 ou un sel d'un tel composé avec un acide minéral ou organique, les nouveaux composés de formule (I) et leur préparation.

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