Piperidine derivatives as nk3 receptor antagonists

Details Piperidine derivatives as nk3 receptor antagonists Piperidine derivatives as nk3 receptor antagonists

C - Chemistry, Metallurgy

07

D

C07D 211/32 (2006.01) A61K 31/4409 (2006.01) A61K 31/4465 (2006.01) A61P 3/04 (2006.01) C07D 401/10 (2006.01) C07D 401/14 (2006.01) C07D 409/14 (2006.01) C07D 413/10 (2006.01) C07D 417/10 (2006.01) C07D 417/14 (2006.01)

Patent

CA 2749650

The present application relates to compounds of formula (I) wherein the definitions are as described in claim 1. It has been found that the present compounds are high potential NK-3 receptor antagonists for the treatment of depression, pain, psychosis, Parkinson's disease, schizophrenia, anxiety and attention deficit hyperactivity disorder (ADHD).

La présente invention concerne des composés de formule (I), dont les définitions sont décrites dans la revendication 1. On a découvert que les présents composés étaient des antagonistes de récepteur NK-3 à haut potentiel pour le traitement de la dépression, de la douleur, de la psychose, de la maladie de Parkinson, de la schizophrénie, de l'anxiété et du trouble déficitaire de l'attention avec hyperactivité (TDAH).

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