A - Human Necessities – 61 – B
Patent
A - Human Necessities
61
B
A61B 19/00 (2006.01) A61K 31/00 (2006.01)
Patent
CA 2320934
A method for treating victims of cerebral edema is presented that includes the intravenous injection of a carbonic anhydrase enzyme inhibitor that passes through the blood-brain barrier, such as acetazolamide (A.K.A., DIAMOX), which is a readily-available and often-prescribed diuretic. Such edema, or brain swelling may be caused as a result of ischemic strokes especially, but also swelling due to tumors, surgeries, or cerebral trauma. It is preferred to combine the a carbonic anhydrase enzyme inhibitor therapy with hyperventilation of the lungs, even including the use of supplemental oxygen, thereby to reduce the concentration of carbon dioxide in the blood and hence in the brain.
L'invention concerne une méthode de traitement de victimes d'oedèmes cérébraux, la méthode consistant à effectuer une injection intraveineuse d'un inhibiteur d'enzyme anhydrase carbonique passant à travers la barrière hémato-encéphalique, tel que l'acétazolamide (A.K.A, DIAMOX?) qui est un diurétique facilement disponible et souvent prescrit. Cet oedème ou gonflement cérébral peut être notamment dû à un infarctus cérébral mais aussi à des tumeurs, des interventions chirurgicales ou un traumatisme cérébral. De préférence, on combine la thérapie par inhibiteur d'enzyme anhydrase carbonique avec une hyperventilation des poumons, comprenant même l'utilisation d'oxygène supplémentaire, afin de réduire la concentration de dioxyde de carbone dans le sang et donc dans le cerveau.
Mccarthy Tetrault Llp
Rodriguez Victorio C.
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