Nicotine-containing granulate

Details Nicotine-containing granulate Nicotine-containing granulate

A - Human Necessities

61

K

A61K 9/16 (2006.01) A61K 31/465 (2006.01)

Patent

CA 2734402

A dust-reduced nicotine-containing granulate comprising a homogenous mixture of nicotine or a pharmaceutically acceptable nicotine derivative and an excipient, the granulate having a particle size of at least 150 µm. Method for the preparation of a dust-reduced nicotine-containing granulate, and use of the nicotine- containing granulate for the preparation of pharmaceutical products.

La présente invention concerne des granulés contenant de la nicotine, à faible teneur en poussières. Ces granulés, qui comprennent un mélange homogène de nicotine ou d'un dérivé nicotinique pharmaceutiquement admis et un excipient, présentent un calibre particulaire d'au moins 150 µm. L'invention concerne également un procédé d'élaboration de tels granulés contenant de la nicotine à faible teneur en poussières, et l'utilisation de tels granulés contenant de la nicotine pour l'élaboration de produits pharmaceutiques.

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