Peptide inhibitors of protein kinase c

Details Peptide inhibitors of protein kinase c Peptide inhibitors of protein kinase c

C - Chemistry, Metallurgy

12

N

C12N 9/12 (2006.01) A61K 38/00 (2006.01) A61K 38/08 (2006.01) A61K 38/10 (2006.01) A61K 38/45 (2006.01) C07K 7/06 (2006.01) C07K 7/08 (2006.01)

Patent

CA 2482598

PKC V5 isozyme-specific peptides are described. The sequences and compositions comprising the sequences are useful for treating diseases states associated with the PKC isozyme from which they are respectively derived. Methods of treatment, pharmaceutical formulations and methods of identifying compounds that mimic the activity of the peptides are also described.

L'invention concerne des peptides spécifiques à l'isozyme PKC V5. Les séquences et les compositions comprenant ces séquences sont utiles dans le traitement d'états pathologiques liés à l'isozyme PKC dont elles sont respectivement dérivées. L'invention concerne également des procédés de traitement, des formulations pharmaceutiques et des procédés d'identification de composés qui imitent l'activité des peptides.

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