N-biarylmethyl aminocycloalkanecarboxamide derivatives

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 417/12 (2006.01) A61K 31/4418 (2006.01) A61K 31/4427 (2006.01) A61K 31/505 (2006.01) A61K 31/506 (2006.01) C07D 213/24 (2006.01) C07D 213/26 (2006.01) C07D 213/61 (2006.01) C07D 239/28 (2006.01) C07D 401/10 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 403/12 (2006.01) C07D 413/10 (2006.01) C07D 413/12 (2006.01)

Patent

CA 2495914

N-Biarylmethylaminocycloalkanecarboxamide derivatives are bradykinin B1 antagonists or inverse agonists useful in the treatment or prevention of symptoms such as pain and inflammation associated with the bradykinin B1 pathway.

Cette invention concerne des dérivés N-Biarylméthylaminocycloalcanecarboxamide qui constituent des antagonistes ou des agonistes inverses de la bradykinine B1 et qui sont utilisés dans le traitement ou la prévention de symptômes tels que la douleur et l'inflammation associés à la voie de la bradykinine B1.

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