Antiparasitic agents

C - Chemistry – Metallurgy – 07 – H

Patent

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Details

C07H 19/01 (2006.01) A01N 43/90 (2006.01) A23K 1/17 (2006.01) A61K 31/70 (2006.01)

Patent

CA 2125690

2125690 9315099 PCTABS00024 Compounds of formula (I) wherein R1 is C1-C6 alkyl, C3-C6 alkenyl, or substituted C1-C4 alkyl wherein said substituent is halo, C1-C4 alkoxy, C2-C5 alkanoyl, C2-C5 alkoxycarbonyl, carboxy, mercapto or aryl; R2 is C3-C8 alkyl, C3-C8 alkenyl, C3-C8 cycloalkyl or C5-C8 cycloalkenyl; R3 is OH, C1-C4 alkoxy or C2-C5 alkanoyloxy; or R3 is linked by a double bond and is =N-OR5 wherein R5 is H, C1-C4 alkyl or C2-C5 alkanoyl; and R4 is HO, C1-C4 alkoxy, C2-C5 alkanoyloxy or halo; or R4 is linked by a double bond and is =O or =N-OR5; or R4 is a group of formula (II) wherein R6 is HO, C1-C4 alkoxy, C2-C5 alkanoyloxy or halo, or R6 is linked by a double bond and is =O or =N-OR5; with certain provisos when R2 is isopropyl or sec-butyl; are broad spectrum antiparasitic agents useful for treating parasite infestations of livestock and domesticated animals.

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