Use of diesters of muramyl peptides in oral form as...

Details Use of diesters of muramyl peptides in oral form as... Use of diesters of muramyl peptides in oral form as...

A - Human Necessities

61

K

A61K 39/39 (2006.01) A61K 38/14 (2006.01)

Patent

CA 2181899

The invention relates to an externally active immunostimulating pharmaceutical composition characterized in that it contains a diester having the general formula (I) wherein R is CH3, X is L-Ala or L-Thr, R1 is a hydrocarbonaceous group having from 1 to 4 carbon atoms, R2 is a hydrocarbonaceous group having 1 or 2 carbon atoms, in an externally administered formulation compatible with an administration of active principle comprised between 0.1 mg and 5 mg par kg of weight to human beings or animals.

L'invention concerne une composition pharmaceutique immunostimulante active par voie externe, caractérisée en ce qu'elle contient un diester de formule générale (I) dans laquelle: R est CH3, X est L-Ala ou L- Thr, R1 est un groupe hydrocarboné possédant de 1 à 4 atomes de carbone, R2 est un groupe hydrocarboné possédant 1 à 2 atomes de carbone, dans une formulation d'administration par voie externe compatible avec une administration de principe actif comprise entre 0,1 mg et 5 mg par kg de poids chez l'homme ou l'animal.

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