Methods and compositions using klotho-fgf fusion polypeptides

Details Methods and compositions using klotho-fgf fusion polypeptides Methods and compositions using klotho-fgf fusion polypeptides

C - Chemistry, Metallurgy

07

K

C07K 14/50 (2006.01) A61K 38/18 (2006.01) C12N 15/62 (2006.01)

Patent

CA 2712634

The present invention is directed to methods, kits and compositions for preventing or treating age-related conditions or metabolic disorders. The Klotho fusion polypeptides of the invention include at least a Klotho protein or an active fragment thereof. The Klotho fusion proteins are useful in the treatment and preventionofa variety of age-related conditions and metabolic disorders.

L'invention concerne des procédés, des trousses et des compositions destinés à prévenir ou traiter des états ou troubles métaboliques liés à l'âge. L'invention porte sur des polypeptides de fusion Klotho qui comprennent au moins une protéine Klotho ou un fragment actif de cette dernière. Les protéines de fusion Klotho précitées sont utilisées pour traiter et prévenir une variété d'états et de troubles métaboliques liés à l'âge.

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