Polypeptide variants with altered effector function

Details Polypeptide variants with altered effector function Polypeptide variants with altered effector function

C - Chemistry, Metallurgy

12

N

C12N 15/13 (2006.01) A61K 39/395 (2006.01) A61P 37/02 (2006.01) C07K 16/00 (2006.01) C07K 16/22 (2006.01) C07K 16/28 (2006.01) C07K 16/42 (2006.01) C12N 15/63 (2006.01) C12P 21/08 (2006.01) G01N 33/577 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2359067

The present invention concerns polypeptides comprising a variant Fc region. More particularly, the present invention concerns Fc region-containing polypeptides that have altered effector function as a consequence of one or more amino acid modifications in the Fc region thereof.

La présente invention concerne des polypeptides comprenant un fragment Fc variant. L'invention concerne plus particulièrement des polypeptides à fragment Fc comportant une fonction effectrice altérée résultant d'une ou plusieurs modifications des acides aminés dans ledit fragment Fc.

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