C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 311/29 (2006.01) A61K 31/195 (2006.01) A61K 31/34 (2006.01) C07C 311/19 (2006.01) C07C 311/42 (2006.01) C07C 311/46 (2006.01) C07C 323/67 (2006.01) C07D 307/12 (2006.01)
Patent
CA 2268103
The present invention relates to compounds that are inhibitors of interleukin- 1.beta. converting enzyme that have Formula (I, II or III). This invention also relates to a method of treatment of stroke, inflammatory diseases, septic shock, reperfusion injury, Alzheimer's disease, and shigellosis, and to a pharmaceutically acceptable composition that contains a compound that is an inhibitor of interleukin-1.beta. converting enzyme.
L'invention concerne des composés inhibiteurs de l'enzyme de conversion de l'interleukine 1 beta , représentés par la formule (I), (II) ou (III). L'invention se rapporte également à une méthode de traitement d'ictus, de maladies inflammatoires, de chocs septiques, de lésions dues à la reperfusion, de la maladie d'Alzheimer et de la shigellose, et à une composition pharmaceutiquement acceptable qui contienne un composé inhibiteur de l'enzyme de conversion de l'interleukine 1 beta .
Allen Hamish John
Brady Kenneth Dale
Harter William Glen
Lunney Elizabeth Ann
Plummer Mark Stephen
Basf Aktiengesellschaft
Macrae & Co.
Warner-Lambert Company
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