C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 213/38 (2006.01) A61K 31/4965 (2006.01) A61K 31/497 (2006.01) A61P 1/00 (2006.01) C07D 295/12 (2006.01) C07D 307/52 (2006.01) C07D 307/81 (2006.01) C07D 317/58 (2006.01) C07D 333/20 (2006.01) C07D 333/28 (2006.01) C07D 333/58 (2006.01) C07D 407/06 (2006.01) C07D 409/06 (2006.01)
Patent
CA 2631693
The present invention relates to novel 3-cyano-naphthalene-1-carboxylic acid perhydroxyalkylmethyl-piperazine compounds of formula I which are antagonistic to tachykinin receptors. The present invention is further directed to pharmaceutical compositions comprising such compounds, to processes for the preparation of such compounds and to intermediate products of these processes.
La présente invention concerne des nouveaux composés d~acide 3-cyano-naphthalène-1-carboxylique perhydroxyalkylméthyl-pipérazine de formule I constituant des antagonistes de récepteurs de la tachykinine. La présente invention concerne également des compositions pharmaceutiques comprenant de tels composés, des procédés de fabrication de tels composés, ainsi que des produits intermédiaires de ces composés.
Antel Jochen
Brueckner Reinhard
Firnges Michael
Jasserand Daniel
Reiche Dania
Mccarthy Tetrault Llp
Solvay Pharmaceuticals Gmbh
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