Antibody treatment of alzheimer's and related diseases

Details Antibody treatment of alzheimer's and related diseases Antibody treatment of alzheimer's and related diseases

C - Chemistry, Metallurgy

12

P

C12P 21/08 (2006.01) A61K 39/395 (2006.01) C12N 5/12 (2006.01)

Patent

CA 2630964

Provided is an antibody that selectively binds to an epitope formed by residues 1-11 o A.beta. in an A.beta. oligomer, a method comprising using the antibody to treat a disease characterize by such an A.beta. amyloid deposit in a patient, and kits comprising same.

La présente invention concerne un anticorps qui se lie sélectivement à un épitope formé par les résidus 1-11 de Aß dans un oligomère Aß, un procédé utilisant l'anticorps pour traiter une maladie caractérisée par un tel dépôt d'amyloïdes Aß chez un patient, et des nécessaires comprenant cet anticorps.

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