Non-adhesive hydrogels

Details Non-adhesive hydrogels Non-adhesive hydrogels

A - Human Necessities

61

L

A61L 15/60 (2006.01) A61F 13/00 (2006.01) A61L 15/22 (2006.01) A61L 15/32 (2006.01) A61M 37/00 (2006.01) C08J 3/28 (2006.01)

Patent

CA 2572297

Substantially non-adhesive hydrogels are useful as wound dressings, wound barriers, therapeutic drug delivery devices and the like. The substantially non-adhesive hydrogels are synthesized by a method that comprises irradiating a solution comprising a biological polymer that is biodegradable and biocompatible, using ionizing radiation, whereby free radicals of the biological polymer are formed and cross-linking occurs between the biological polymer radicals to provide the hydrogel.

La présente invention concerne des hydrogels non adhésifs convenant comme pansements, barrières pour lésions, dispositifs thérapeutique d'administration de médicaments, et analogues. Ces hydrogels sensiblement non adhésifs s'obtiennent par synthèse. En l'occurrence, on prend une solution comprenant un polymère biologique qui soit biodégradable et biocompatible, et on la soumet à un rayonnement ionisant. Il en résulte une formation de radicaux libres du polymère biologique et une réticulation entre les radicaux de polymère biologique, ce qui donne l'hydrogel.

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