C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 295/26 (2006.01) A61K 31/495 (2006.01) C07D 207/16 (2006.01) C07D 207/277 (2006.01) C07D 211/58 (2006.01) C07D 211/60 (2006.01) C07D 211/62 (2006.01) C07D 213/38 (2006.01) C07D 213/74 (2006.01) C07D 233/54 (2006.01) C07D 241/08 (2006.01) C07D 303/34 (2006.01) C07D 309/14 (2006.01) C07D 335/02 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01) C07D 405/12 (2006.01) C07D 409/12 (2006.01) C07D 453/02 (2006.01)
Patent
CA 2078263
79/FPG42 80/FPG43 88/FPG50 18448 TITLE OF THE INVENTION SUBSTITUTED ALKYL DERIVATIVES OF PIPERIZINYLCAMPHORSULFONYL OXYTOCIN ANTAGONISTS ABSTRACT OF THE INVENTION Compounds of the formula: Image where R is substituted or unsubstituted alkyl. 79/FPG42 - ii - 18448 The compounds of formula I are oxytocin antagonists useful in the treatment of preterm labor, dysmenorrhea and for the stoppage of labor preparatory to cesarean delivery. Also disclosed are pharmaceu- tical compositions containing these compounds, methods of their use and methods of their preparation.
Erb Jill M.
Hoffman James B.
Perlow Debra S.
Williams Peter D.
Merck & Co. Inc.
Swabey Ogilvy Renault
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