Method and nucleic acids for the differentiation of prostate...

Details Method and nucleic acids for the differentiation of prostate... Method and nucleic acids for the differentiation of prostate...

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) B01J 19/00 (2006.01)

Patent

CA 2445731

The present invention relates to chemically modified genomic sequences, to oligonucleotides and/or PNA-oligomers for detecting the cytosine methylation state of genomic DNA, as well as to a method for ascertaining genetic and/or epigenetic parameters of genes for use in characterisation, classification, differentiation, diagnosis and therapy of prostate lesions.

La présente invention concerne des séquences génomiques chimiquement modifiées, des oligonucléotides ou des oligomères de la protéine PNA permettant la détection de l'état de méthylation de la cytosine de l'ADN génomique, ainsi qu'un procédé permettant la détermination de paramètres génétiques et/ou épigénétiques de gènes utiles dans la caractérisation, la classification, la différenciation, le diagnostic et le traitement des lésions prostatiques

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